MRCP UK EXAMINATIONS

Detailed explanation-1: -Kupffer cells are resident liver macrophages and play a critical role in maintaining liver functions. Under physiological conditions, they are the first innate immune cells and protect the liver from bacterial infections.

Detailed explanation-2: -Kupffer cells are macrophages that are fixed within the sinusoids of the liver. They are the body’s most abundant source of fixed macrophages.

Detailed explanation-3: -Macrophages represent by far the most abundant immune cells in the liver. Hepatic macrophages are still often referred as Kupffer cells (KCs) that indeed represent the major fraction of liver macrophages.

Detailed explanation-4: -Kupffer cells (also known as stellate sinusoidal macrophages or Kupffer-Browicz cells) are macrophages found in the sinusoids of the liver.