MRCP UK EXAMINATIONS

Detailed explanation-1: -Pancreatic juice is secreted into the duodenum through duodenal papillae. Some individuals have also an accessory duct, named accessory pancreatic duct, which may be functional (that is, it also empties the contents of the exocrine pancreas into the duodenum) or non-functional.

Detailed explanation-2: -The pancreatic duct delivers exocrine secretions into the duodenum. The ductal cells secrete fluid and bicarbonate ions, which neutralize acinar cell secretions, as well as the acidic gastric contents entering the duodenum (110).

Detailed explanation-3: -HCO3–-rich fluid in the pancreatic juice (2 3 L/day) is secreted by epithelial cells lining the pancreatic duct tree, while digestive enzymes are secreted by acinar cells with a small amount of Cl–-rich fluid.

Detailed explanation-4: -The pancreas secretes digestive enzymes into the duodenum and hormones into the bloodstream. The digestive enzymes (such as amylase, lipase, and trypsin) are released from the cells of the acini and flow into the pancreatic duct.