MRCP UK EXAMINATIONS

ABDOMINAL

GASTROINTESTINAL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following hormones is released by the presence of fat and protein in the small intestine and has major effect to decrease gastric emptying?
A
Cholecystokinin (CCK)
B
Gastrin
C
Glucose Dependent Insulinotorphic Peptide (GIP)
D
Secretin
Explanation: 

Detailed explanation-1: -The presence of fat, such as oleate, in the meal results in stimulation of cholecystokinin (CCK) secretion in the duodenum; in turn, this inhibits antral motility, stimulates pyloric tone and delays gastric emptying [8]. CCK is the first of a repertoire of hormones that regulate gastric emptying.

Detailed explanation-2: -Cholecystokinin stimulates the gallbladder to contract and release stored bile into the intestine.

Detailed explanation-3: -Cholecystokinin (CCK) is known to inhibit gastric acid secretion and gastric emptying but its physiological role in the inhibition of gastric functions is not settled.

There is 1 question to complete.