MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
. A 23-years-old male presented to his physician with excess of the somatotropic hormone, the enlarged nose, lips, ears, a mandible, hands and feet. What is the most likely diagnosis?
A
Acromegaly
B
Pituitary nanism
C
Itsenko-Cushing disease
D
Addison’s disease
Explanation: 

Detailed explanation-1: -In more than 9 out of 10 cases, acromegaly is caused by a tumor in the pituitary gland, called a pituitary adenoma. More rarely, the cause may be a tumor in another part of the body. Although scientists don’t know what causes these tumors to develop, genetic factors may play a role.

Detailed explanation-2: -Gigantism and acromegaly are syndromes of excessive secretion of growth hormone (hypersomatotropism) that are nearly always due to a pituitary adenoma. Before closure of the epiphyses, the result is gigantism. Later, the result is acromegaly, which causes distinctive facial and other features.

There is 1 question to complete.