ABDOMINAL
GENERALISED LYMPHADENOPATHY
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Question
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A 26-year-old patient arrived in a hospital with complaints to a fever and weakness. One of the enlarged cervical lymph nodes was taken for histological study. Microscopical investigation showed in lymphoid tissue the centers of necrosis, surrounded with epithelioid cells, giant multinuclear Pirogov-Langhans cells and lymphocytes. What is the most likely disease?
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Tuberculosis
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Lymphogranulomatosis (Hodgkin’s disease)
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Lymphatic leukemia
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Sarcoidosis (Boeck’s disease)
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Explanation:
Detailed explanation-1: -Cell Injury. This is the gross appearance of caseous necrosis in a hilar lymph node infected with tuberculosis. The node has a cheesy tan to white appearance. Caseous necrosis is really just a combination of coagulative and liquefactive necrosis that is most characteristic of granulomatous inflammation.
Detailed explanation-2: -The symptomatology is acute with fever and painful, erythematous lumps over the neck. Tuberculous cervical lymphadenitis (also known as scrofula) is caused by Mycobacterium tuberculosis and presents with malaise, weight loss, and nontender neck lumps.
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