ABDOMINAL
GENERALISED LYMPHADENOPATHY
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Question
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A 52-year-old woman, with a medical history of the menstrual cycle disturbances and hemorrhages, had curettage of the uterine cavity. Histological investigation revealed the increased quantity of the endometrial glands. Many glands had a morphological pattern of a proliferation phase, clumped together and had intraglandular papillary protrusions. Some glandular cells exhibited the signs of nuclear and cytoplasm polymorphism. What is the most likely diagnosis?
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Atypical hyperplasia of endometrium
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Cystic glandular hyperplasia of endometrium
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Glandular hyperplasia of endometrium
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Glandular polyp of endometrium
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Explanation:
Detailed explanation-1: -In an endometrial biopsy, a small piece of tissue from the lining of the uterus (the endometrium) is removed and examined under a microscope for cancer and other cell irregularities. The procedure helps find the cause of a woman’s heavy or irregular bleeding.
Detailed explanation-2: -The term dysfunctional uterine bleeding (DUB) refers to any abnormal bleeding from the uterus, unassociated with tumour, inflammation and pregnancy. The histological diagnosis of DUB is very essential for adequate management especially in perimenopausal and postmenopausal females.
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