MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A 42-year-old man presented with a thyroid gland enlargement in two times. A physical investigation revealed firm, irregular lobulated gland. Histological investigation showed a diffusive infiltration of thyroid gland by lymphocytes, plasmocytes with follicles formation and the enhanced growth of a connective tissue. What is the most likely diagnosis?
A
Hashimoto’s goiter.
B
Endemic goiter
C
Sporadic goiter.
D
Diffuse toxic goiter.
Explanation: 

Detailed explanation-1: -High quantities of iodine are found in a number of drugs such as Amiodarone, Lugol’s solution (iodine), some cough syrups and contrast dyes used for some types of scans. This might cause the thyroid to produce either too much or too little thyroid hormones in some individuals.

Detailed explanation-2: -If the thyroid were to develop abnormally and lack most of its extracellular folds, secretion of calcitonin would be severely below normal. A hormone has a half-life of 20 minutes.

There is 1 question to complete.