ABDOMINAL
HEMOGLOBINOPATHY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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two alpha-globin subunits and two gamma-globin subunits
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two alpha-globin subunits and two beta-globin subunits
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two alpha-globin subunits and two delta-globin subunits
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two alpha-globin subunits and one beta-globin subunit
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Detailed explanation-1: -Beta-globin is a component (subunit) of a larger protein called hemoglobin, which is located inside red blood cells. In adults, hemoglobin consists of four protein subunits: usually two subunits of beta-globin and two subunits of a protein called alpha-globin, which is produced from another gene called HBA.
Detailed explanation-2: -HbA, the most common adult form of hemoglobin, comprises two alpha and two beta-globin subunits.
Detailed explanation-3: -The composition of the four globin chains determines the hemoglobin type. Fetal hemoglobin (HbF) has two alpha and two gamma chains (alpha2 gamma2). Adult hemoglobin A (HbA) has two alpha and two beta chains (alpha2 beta2), whereas hemoglobin A2 (HbA2) has two alpha and two delta chains (alpha2 delta2).