ABDOMINAL
HEMOGLOBINOPATHY
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Question
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microcytic hypochromatic hemolytic anemia, abnormal peripheralblood smear with nucleated red blood cells, reduced amounts of HbA, severe anemia, hepatosplenomegaly, fail to thrive, become progressively pale, regular bloodtransfusion are necessary, and usually come to medical attention between 6 months S2 years of age.
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Thalassemia major
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Thalassemia intermedia
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Thalassemia minor
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Sickle cell disease
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Explanation:
Detailed explanation-1: -Beta-thalassemia (-thalassemia) is characterized by reduced synthesis of the hemoglobin subunit beta (hemoglobin beta chain) that results in microcytic hypochromic anemia, an abnormal peripheral blood smear with nucleated red blood cells, and reduced amounts of hemoglobin A (HbA) on hemoglobin analysis.
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