MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cells containing large amounts of Hb S sickle when which of the following conditions occur?
A
high oxygen tension, and acidosis
B
hypoxia and alkalosis
C
temperatures <37 C and alkalosis
D
temperatures>37 C and hypoxia
Explanation: 

Detailed explanation-1: -Make sure you know when to get medical advice and where to go, as sickle cell disease can cause a number of serious problems that can appear suddenly. Problems to look out for include: a high temperature over 38C (or any increased temperature in a child) severe pain that’s not responding to treatment at home.

Detailed explanation-2: -When oxygen levels inside a red blood cell get low, the defective hemoglobin forms long rods. These rods stretch the red blood cells into long, abnormal “sickle” shapes.

There is 1 question to complete.