MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Hemoglobin present on electrophoresis for homozygous sickle cell disease?
A
HbA, S, F, A2
B
HbS, F, A2
C
HbA, E, F, A2
D
HbA, C, F
Explanation: 

Detailed explanation-1: -Hemoglobin electrophoresis is used as a screening test to identify normal and abnormal hemoglobins and assess their quantity. Hemoglobin types include hemoglobin A1 (HbA1), hemoglobin A2 (HbA2), hemoglobin F (HbF; fetal hemoglobin), hemoglobin C (HbC), and hemoglobin S (HbS).

Detailed explanation-2: -Hemoglobin Type F (HgbF): Normally, this hemoglobin type accounts for the largest part of red blood cells in fetuses, babies and children up to age 3. A high type F hemoglobin level in adults is considered an abnormal hemoglobin level. Hemoglobin Type S (HgbS): This hemoglobin type is a symptom of sickle cell anemia.

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