ABDOMINAL
THALASSEMIA
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
Hb H is composed of
|
|
Two a and two b chains
|
|
|
Two e and two g chains
|
|
|
Four b chains
|
|
|
Four g chains
|
Explanation:
Detailed explanation-1: -HbH disease is usually caused by inactivation of three alpha-globin alleles leading to underproduction of alpha-globin chains of Hb, with the formation of beta-4 tetramers (HbH).
Detailed explanation-2: -Hemoglobin is an oxygen-binding protein found in erythrocytes that transports oxygen from the lungs to tissues. Each hemoglobin molecule is a tetramer made of four polypeptide globin chains.
Detailed explanation-3: -Hemoglobin consists of an iron-containing heme ring and four globin chains: two alpha and two nonalpha. The composition of the four globin chains determines the hemoglobin type.
There is 1 question to complete.