MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
List two sets of lab data that can distinguish IDA from beta thalassemia trait.
A
Serum iron and RBC
B
Hgb and Hct
C
WBC and RDW
D
RBC indices and Platelets
Explanation: 

Detailed explanation-1: -Similarly, in some equipped laboratories comprehensive DNA analysis and Hb electrophoresis are used for diagnosis of -thalassemia trait (7). Diagnosis of iron deficiency anemia can be performed easily through the routine CBC test or iron and serum ferritin measurements (7).

Detailed explanation-2: -Iron deficiency and -thalassemia minor are best differentiated using the serum ferritin level, serum iron level, total iron-binding capacity, transferrin saturation, and Hb A2 level, along with a CBC and examination of a peripheral blood film (Table 17.1).

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