ABDOMINAL
THALASSEMIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Imbalance globin chain synthesis refers to the imbalance between globin chain synthesis between
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True
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False
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -Beta-globin is a component (subunit) of a larger protein called hemoglobin, which is located inside red blood cells. In adults, hemoglobin consists of four protein subunits: usually two subunits of beta-globin and two subunits of a protein called alpha-globin, which is produced from another gene called HBA.
Detailed explanation-2: -Alpha thalassemia is the result of deficient or absent synthesis of alpha globin chains, leading to excess beta globin chains. Alpha globin chain production is controlled by two genes on each chromosome 16 (Table 14, 5). Deficient production is usually caused by a deletion of one or more of these genes.
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