MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In the consideration of guaranteeing HC, if the mother, the Hb-typing result is Hb E trait (born from the Beta line) and the father, the Hb-typing result is the Hb H trait (born from the Alpha line), there will be a tendency for how to consider
A
Not accepting HC, receiving life STD because parents are only carriers of thalassemia, but they are different types.
B
Receiving HC Receiving Life STD as both parents are thalassemia carriers
C
Patients with HC cannot consider Life as both parents are thalassemia carriers.
D
Not receiving HC and still unable to consider life because both parents are thalassemia carriers. CBC and Hb-typing blood tests must be informed first.
Explanation: 

Detailed explanation-1: -In Hb EE, the electrophoresis generally indicates 90% or more Hb E with a mild elevation in Hb F. Hb E +-thalassemia may have an extremely variable laboratory picture. They usually have a mild anemia of approximately 9.5 g/dL. However, significant ranges of anemia has been observed, with Hb as low as 5.7 g/dL.

Detailed explanation-2: -If both parents have the beta thalassaemia trait, there’s a: 1 in 4 chance each child they have will not inherit any faulty genes and will not have thalassaemia or be able to pass it on. 1 in 2 chance each child they have will just inherit a copy of the faulty gene from 1 parent and be a carrier.

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