ABDOMINAL
THALASSEMIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Label each part of the Sickled RBC.
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Deoxy-HbS polymer
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HbSS RBC
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Oxy-SS RBC
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Vaso-occlusion
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Oxy-HbS Monomer
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Explanation:
Detailed explanation-1: -Haemoglobin is a hetero-tetramer, consisting of two alpha subunits and two beta subunits (a “dimer of dimers"), the alpha subunits (141 residues in human haemoglobin) and beta subunits (146) being homologous. This form is called haemoglobin A.
Detailed explanation-2: -Sickle cell disease is caused by a variant of the beta-globin gene called sickle hemoglobin (Hb S).
There is 1 question to complete.