ABDOMINAL
THALASSEMIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Structurally abnormal hemoglobins
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Absent or defective synthesis of a polypeptide chain in hemoglobin
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Excessive absorption of iron
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Abnormal or defective protoporphyrin synthesis
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Detailed explanation-1: -Thalassemia is the result of the deficient synthesis of one of the polypeptide chains of the hemoglobin molecule. As a result, the ability of red blood cells to transport oxygen in the body is reduced. Depending upon its degree of severity, thalassemia may be major, minor, or intermedia.
Detailed explanation-2: -Thalassemias are a heterogeneous grouping of genetic disorders that result from a decreased synthesis of alpha or beta chains of hemoglobin (Hb). Hemoglobin serves as the oxygen-carrying component of the red blood cells. It consists of two proteins, an alpha, and a beta.
Detailed explanation-3: -The thalassemias are a group of inherited hematologic disorders caused by defects in the synthesis of one or more of the hemoglobin chains. Alpha thalassemia is caused by reduced or absent synthesis of alpha globin chains, and beta thalassemia is caused by reduced or absent synthesis of beta globin chains.
Detailed explanation-4: -Hemoglobin molecules are made of chains called alpha and beta chains that can be affected by mutations. In thalassemia, the production of either the alpha or beta chains are reduced, resulting in either alpha-thalassemia or beta-thalassemia.