MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Reversible pathophysiology of SCD is in the presence of oxygen bond only for a certain amount of time.
A
True
B
False, it stays for a long time
C
False
D
None of the above
Explanation: 

Detailed explanation-1: -Sickle cell disease is an inherited blood disorder marked by defective hemoglobin. It inhibits the ability of hemoglobin in red blood cells to carry oxygen. Sickle cells tend to stick together, blocking small blood vessels causing painful and damaging complications.

Detailed explanation-2: -Sickled forms were classified as reversible if they were normochromic and the abnormal shape had a holly leaf, splinter, boat, envelope or ellipsoid configuration. Irreversible sickled cells have deformed membranes that have lost the capacity to return to a normal shape even on exposure to oxygen [4.

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