MRCP UK EXAMINATIONS

Detailed explanation-1: -Approximately 70, 000 to 100, 000 Americans have sickle cell disease, the most common form of an inherited blood disorder. This disease, which is present in affected individuals at birth, causes the production of abnormal hemoglobin.

Detailed explanation-2: -There are about 100, 000 people in the United States. Worldwide there are about 300, 000 babies born [with sickle cell disease] every year, and the majority in low-income countries will pass away before their fifth birthday.

Detailed explanation-3: -The prevalence rates of sickle cell trait in the United States is 9% among African American which is about 3 million people, and 0.2% among Caucasians. [2] Worldwide, it is estimated that there are 300 million people with sickle cell trait and one-third of this number are in sub-Saharan Africa.