MRCP UK EXAMINATIONS

Detailed explanation-1: -Mild forms of thalassemia trait don’t need treatment. For moderate to severe thalassemia, treatments might include: Frequent blood transfusions. More severe forms of thalassemia often require frequent blood transfusions, possibly every few weeks.

Detailed explanation-2: -Children with alpha thalassemia trait or who are carriers don’t need treatment. Children and adults with alpha thalassemia major need lifelong medical care that includes: blood transfusions about every 2–4 weeks. medicines to remove extra iron from their bodies (called chelation)

Detailed explanation-3: -Thalassemia minor is clinically asymptomatic but some subjects may have moderate anemia. Beta-thalassemias are caused by point mutations or, more rarely, deletions in the beta globin gene on chromosome 11, leading to reduced (beta+) or absent (beta0) synthesis of the beta chains of hemoglobin (Hb).