MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

ANKYLOSING SPONDYLITIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
· Symptomatic regardless of predominant manifestations:tried min 2 NSAIDs · Active. Moderate/more severe disease (BASDAI 4/>, PGS min2) à yr/ added with:Peripheral dominant:SSZ / MTX Axial dominant:anti TNF-ɑ IBD:monoclonal antibody Is this statement correct?
A
Can be both
B
Correct
C
Salah
D
None of the above
Explanation: 

Detailed explanation-1: -The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) has been widely utilized to evaluate disease activity in patients with ankylosing spondylitis (AS) by an arbitrary cut-off of ≥4 to indicate high disease activity and initiate biological therapy.

Detailed explanation-2: -The BASDAI or Bath Ankylosing Spondylitis Disease Activity Index is a validated diagnostic test which allows a physician, usually a rheumatologist, to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of Ankylosing spondylitis (AS).

Detailed explanation-3: -NSAIDs Reduce Inflammation Those used to treat ankylosing spondylitis include: Indomethacin (Indocin) Ibuprofen (Motrin, Advil) Naproxen (Aleve, Naprosyn)

Detailed explanation-4: -Ankylosing spondylitis (AS) is a long-term (chronic) condition in which the spine and other areas of the body become inflamed. The symptoms of AS can vary but usually involve: back pain and stiffness that improves with exercise and isn’t relieved by rest.

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