MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

ANTICOAGULATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
About heparin-induced thrombocytopenia (HIT):
A
Type 1 HIT is benign
B
Type 2 HIT is benign
C
Type 1 HIT can cause thrombosis
D
Type 2 HIT can cause thrombosis
E
HIT type 2 requires treatment discontinuation
Explanation: 

Detailed explanation-1: -Treatment of HIT entails immediate withdrawal of all heparin, including heparin-containing flushes and catheters. Heparin cessation alone, however, is often insufficient to prevent thrombosis.

Detailed explanation-2: -Following an episode of HIT, IgG antibodies may remain in the system for up to 100 days (median of 85 days); if the patient receives any amount of UFH or LMWH during this period, platelet counts can drop in as little as 12 hours.

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