MRCP UK EXAMINATIONS

Detailed explanation-1: -Warfarin-induced submandibular hematoma can cause airway obstruction. In these patients, early definitive airway management is crucial. A rapid medical management is also crucial to reverse the effects of warfarin.

Detailed explanation-2: -Warfarin has to be stopped, and parenteral vitamin K and fresh frozen plasma have to be administered. The most rapid way of reversing the anticoagulant effect of warfarin is by transfusing fresh frozen plasma.

Detailed explanation-3: -Vitamin K antagonists such as warfarin inhibit VKOR to disrupt the vitamin K cycle, resulting in undercarboxylation of vitamin K–dependent proteins and lowering the functional levels of vitamin K–dependent blood coagulation proteins.