MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

ANTICOAGULATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the Recommended amount of EDTA used as anticoagulants
A
1.5 +-0.25mg/ml of blood
B
1.3+-0.25mg/ml of blood
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Therefore, dipotassium EDTA is recommended as the anticoagulant of choice in specimen collection for blood cell counting and sizing. The amount of dipotassium EDTA used is 1.5-2.2 mg (3.7-5.4 mumol) per milliliter of blood.

Detailed explanation-2: -The optimal concentration is 1.5 mg per ml of blood. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts.

Detailed explanation-3: -The EDTA BD Vactutainer® brand sterile hematology tubes contain 1.8 mg EDTA per mL blood. Thus, we have a ratio of EDTA to iron 1.8/0.42 simplified to 4.3/1.

Detailed explanation-4: -The Titration The burettte is filled with an EDTA solution of known concentration. Concentrations of 0.010 mol L-1 are commonly used.

There is 1 question to complete.