CLINICAL ENCOUNTERS
ANTICOAGULATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The risk of bleeding is great and not worth it
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It is synergistic and worthwhile to protect against reoccurrences of thrombosis
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Either A or B
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None of the above
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Detailed explanation-1: -When combined, these medications increase the risk of significant bleeding complications. Recent studies have compared different combinations of antiplatelet and anticoagulant medications for a variety of cardiovascular conditions.
Detailed explanation-2: -The combination of anticoagulant and antiplatelet therapy is more effective than antiplatelet therapy alone for the initial and long-term management of acute coronary syndromes but increases the risk of bleeding.
Detailed explanation-3: -Temporary combination of antiplatelet and anticoagulant drugs is usually necessary after coronary intervention in patients with atrial fibrillation.
Detailed explanation-4: -Aspirin 100 mg monotherapy and DAPT are associated with the highest risk of bleeding. Although this exists regardless of the duration of antiplatelet therapy, it is highest during the duration extending between three months and one year post initiation of antiplatelet therapy.
Detailed explanation-5: -Practice points to avoid the risk of bleeding Advise patients to avoid low-dose aspirin and other NSAIDs while taking an oral anticoagulant. Encourage patients to see a health professional if they have any unexplained bruising or bleeding, or pink, red or dark-brown urine.