MRCP UK EXAMINATIONS

Detailed explanation-1: -Platelets, which circulate within the blood, are the essential mediators that trigger the mechanical pathway of the coagulation cascade upon encountering any damage to the blood vessels. Platelets encourage primary hemostasis via three major processes: activation, adhesion and aggregation.

Detailed explanation-2: -These drugs are used in the prophylaxis of venous thromboembolic disease (VTE) on acute or elective admission to the hospital, and they are used in the treatment of deep vein thromboses (DVT) and pulmonary embolism (PE).

Detailed explanation-3: -Structure and Mechanism of Action Both heparin and LMWH exert their anticoagulant activity by activating antithrombin (earlier called antithrombin III), which accelerates the inactivation of coagulation enzymes thrombin (factor IIA), factor Xa and factor IXA.