MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

ANTICOAGULATION

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

Mr Izka is going to run a test that will determine the rate of blood cell precipitate in one hour. What type of anticoagulant that used in this test?

A	sodium citrate
B	heparin
C	plain tube
D	oxalate

Explanation:

Detailed explanation-1: -Mostly potassium EDTA is used as an anticoagulant, recommended for hematology studies.

Detailed explanation-2: -The “citrate tube” is for collecting blood for performing coagulation studies. It contains 3.2% sodium citrate as its anticoagulant. [3] Mixing the blood inside the tube a few times is also recommended to form the plasma. There is no anticoagulant or additive inside the tube.

Detailed explanation-3: -Abstract. Background: Sodium citrate has been used as an anticoagulant to stabilize blood and blood products for over 100 years, presumably by sequestering Ca(++) ions in vitro. Anticoagulation of blood without chelation can be achieved by inhibition of the contact pathway by corn trypsin inhibitor (CTI).

Detailed explanation-4: -It is used in medicine to prevent blood samples from clotting and to remove calcium and lead from the body. It is also used to keep bacteria from forming a biofilm (thin layer stuck to a surface). It is a type of chelating agent. Also called edetic acid and etheylenediaminetetraacetic acid.

There is 1 question to complete.