MRCP UK EXAMINATIONS

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CLINICAL ENCOUNTERS

ANTICOAGULATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which pathway of coagulation is slow process and how many time it takes to initiation of blood clotting
A
PTT, 15-20 sec
B
PT, 2-6 min
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Normal PTT values can vary between laboratories but 25 to 35 seconds is considered normal.

Detailed explanation-2: -As with the PT test, a higher PTT number means your blood is taking longer than usual to clot. A lower PTT number means that your blood is clotting faster than normal.

Detailed explanation-3: -Description. Partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT) are used to test for the same functions; however, in aPTT, an activator is added that speeds up the clotting time and results in a narrower reference range.

Detailed explanation-4: -The prothrombin time is a measure of the integrity of the extrinsic and final common pathways of the coagulation cascade. This consists of tissue factor and factors VII, II (prothrombin), V, X, and fibrinogen.

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