MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

DIABETIC RETINOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following are the findings from DRESS study? (multiple selection)
A
There is a significant statistical difference in the improvement of hard exudates
B
Oral sulodexide therapy over 12 months improved macular hard exudates in patients with mild-to-moderate NPDR
C
There are no statistical difference in the adverse effects among sulodexide and placebo
D
Placebo has more side effect compared to sulodexide group
Explanation: 

Detailed explanation-1: -Sulodexide (SDX) belongs to a class of substances known as glycosaminoglycans (GAGs).

Detailed explanation-2: -Clinical reports of the use of sulodexide, a preparation of low molecular weight glycosaminoglycan polysaccharides, have shown that proteinuria is significantly diminished in patients with diabetic nephropathy, even when these patients are receiving either an ACE inhibitor or angiotensin receptor antagonist.

There is 1 question to complete.