CLINICAL ENCOUNTERS
RHEUMATOID ARTHRITIS
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
Immunological testing of anti-citrullinated peptide antibodies (ACPA) is most commonly used for the diagnosis and prognosis of which immunological condition?
|
|
Ankylosis spondylitis
|
|
|
Rheumatoid arthritis
|
|
|
Psoriatic arthritis
|
|
|
Systemic lupus erythematosus
|
|
|
Reiter’s syndrome
|
Explanation:
Detailed explanation-1: -The presence of anti-citrullinated protein autoantibodies (ACPA) is a hallmark feature of rheumatoid arthritis (RA), which causes chronic joint destruction and systemic inflammation. Based on ACPA status, RA patients can be sub-grouped into two major subsets: ACPA-positive RA (ACPA+ RA) and ACPA-negative RA (ACPA– RA).
Detailed explanation-2: -Rheumatoid factor Despite its relatively low specificity, the presence of RF is widely used as a diagnostic marker for RA. RFs are antibodies directed to the crystallizable fragment of IgG molecules.
There is 1 question to complete.