MRCP UK EXAMINATIONS

NEUROLOGY

PARKINSON S DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A commonly used and effective medication for Parkinson’s Disease is ____ which is converted to ____ by neurons.
A
dopamine; L-dopa
B
botox, acetylcholine
C
acetylcholine; L-dopa
D
L-dopa, dopamine
Explanation: 

Detailed explanation-1: -Levodopa is the precursor to dopamine. Most commonly, clinicians use levodopa as a dopamine replacement agent for the treatment of Parkinson disease.

Detailed explanation-2: -In patients with Parkinson’s disease, there is not enough dopamine in some parts of the brain. Levodopa enters the brain and helps replace the missing dopamine, which allows people to function better.

Detailed explanation-3: -In the brain, L-DOPA is handled as if it were naturally produced. It is taken up into dopaminergic nerve terminals where it is briefly stored before being converted into dopamine and released upon nerve stimulation.

Detailed explanation-4: -Levodopa (also called L-dopa) is the most commonly prescribed and most effective medicine for controlling the symptoms of PD, particularly bradykinesia and rigidity.

There is 1 question to complete.