MRCP UK EXAMINATIONS

Detailed explanation-1: -In identical twins, if a twin develops schizophrenia, the other twin has a 1 in 2 chance of developing it, too. This is true even if they’re raised separately.

Detailed explanation-2: -[2] Analyzing classic studies of the genetics of schizophrenia done as early as in 1930s, Fischer concludes that a concordance rate for psychosis of about 50% in monozygotic twins seems to be a realistic estimate, which is significantly higher than that in dizygotic twins of about 10–19%.

Detailed explanation-3: -Mirror image: Identical twins are believed to be genetically identical, but one twin can have mutations not shared by the other. Identical twins can be genetically different, which could explain why they do not always share disorders such as schizophrenia or autism, according to a study published in March in PLoS One.

Detailed explanation-4: -Schizophrenia and heredity The risk jumps to 50 percent if both parents have been diagnosed with schizophrenia, while the risk is 40 to 65 percent if an identical twin has been diagnosed with condition.