MRCP UK EXAMINATIONS

Detailed explanation-1: -Megaloblastic anemia is caused in part by vitamin B12 deficiency. Left untreated, vitamin B12 deficiency can cause neurological issues, including memory loss, problems with balance and paresthesia, which is a sense of tingling or prickling in your arms and legs.

Detailed explanation-2: -The initial evaluation for megaloblastic anemia includes a CBC and review of a peripheral blood smear. Additional testing for vitamin B12 and/or folate deficiency and antibody testing for pernicious anemia may be performed based on the results of these initial tests.

Detailed explanation-3: -Common physical examination findings of megaloblastic anemia include glossitis, pallor, mouth ulcers, vitiligo, subacute combined degeneration, and positive Romberg’s sign.