MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A patient with polycythemia vera has a highRBC count and is at risk for the development of thrombosis. Which treatment is important to reduce blood viscosity and to deplete the patient’s iron stores?

A	Blood transfusions
B	Radiation
C	Chelation therapy
D	Phlebotomy

Explanation:

Detailed explanation-1: -The most common treatment for polycythemia vera is having frequent blood withdrawals, using a needle in a vein (phlebotomy). It’s the same procedure used for donating blood. This decreases your blood volume and reduces the number of excess blood cells.

Detailed explanation-2: -Abstract. Ropeginterferon alfa-2b-njft (Besremi) is the first interferon for treating polycythemia vera and the first approved medication for this condition that can be taken regardless of the patient’s treatment history.

Detailed explanation-3: -Phlebotomy should be started by withdrawing 250 to 500 cc of blood daily or every other day until a hematocrit between 0.4 and 0.45 (40% and 45%) is obtained. In the elderly or those with a cardiovascular disease, a smaller amount of blood (200 to 300 cc) should be withdrawn twice weekly.

Detailed explanation-4: -Polycythemia vera (pol-e-sy-THEE-me-uh VEER-uh) is a type of blood cancer. It causes your bone marrow to make too many red blood cells. These excess cells thicken your blood, slowing its flow, which may cause serious problems, such as blood clots.

There is 1 question to complete.