MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the function of the blood-brain barrier?
A
This barrier is formed by the endothelial cells of the brain’s capillaries, which form continuous tight junctions, creating a barrier to macromolecules and many compounds.
B
The autonomic nervous system regulates the activities of internal organs such as the heart, lungs, blood vessels, digestive organs, and glands. Maintenance and restoration of internal homeostasis is largely the responsibility of the autonomic nervous system
C
Flaccid paralysis and atrophy of the affected muscles.
D
Destruction or dysfunction of the basal ganglia leads not to paralysis but to muscle rigidity, disturbances of posture, and difficulty initiating or changing movement.
Explanation: 

Detailed explanation-1: -In the capillaries that form the blood–brain barrier, endothelial cells are wedged extremely close to each other, forming so-called tight junctions. The tight gap allows only small molecules, fat-soluble molecules, and some gases to pass freely through the capillary wall and into brain tissue.

Detailed explanation-2: -The endothelial monolayer of the brain capillaries serves both as a crucial interface for exchange of nutrients, gases, and metabolites between blood and brain, and as a barrier for neurotoxic components of plasma and xenobiotics.

Detailed explanation-3: -Which of the following is the function of the blood-brain barrier created by glia in the brain? It protects the brain from potentially toxic chemicals circulating in the blood.

Detailed explanation-4: -What is the purpose of the blood–brain barrier? It transmits electrical signals between neurons. It supplies nutrients while preventing hazardous chemicals from reaching the brain.

There is 1 question to complete.