MRCP UK EXAMINATIONS

NEUROLOGY

SURGERY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which patient assessed by the nurse is at greatest risk for the development of myelo-dysplastic syndromes (MDSs)?
A
A 24-year-old female taking oral contraceptives
B
A 40-year-old patient with a history of hypertension
C
A 52-year-old patient with acute kidney injury
D
A 72-year-old patient with a history of cancer
Explanation: 

Detailed explanation-1: -Older age. Older age is one of the most important risk factors for MDS. MDS is uncommon in people younger than 50, and most cases are found in people in their 70s or 80s.

Detailed explanation-2: -MDS occurs most often in people older than 60 and is less common in younger people. MDS is rare in children. Gender. Men develop MDS more often than women.

Detailed explanation-3: -This syndrome is caused by inherited changes in the RUNX1 gene. Normally, this gene helps control the development of blood cells. Changes in this gene can lead to blood cells not maturing like they normally would, which can increase the risk of developing MDS.

Detailed explanation-4: -Higher-risk myelodysplastic syndromes (MDS) are defined by patients who fall into higher-risk group categories in the original or revised International Prognostic Scoring System. Survival for these patients is dismal, and treatment should be initiated rapidly.

There is 1 question to complete.