RESPIRATORY
CHRONIC OBSTRUCTIVE PULMONARY DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Indicated when PaO2 <50 mmHg or SaO2 <88%
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Indicated when PaO2 > 55 mmHg but < 60 mmHg associated with left heart failure or polycythemia
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The goal is to keep SaO2
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After 60-90 days, the effectiveness of oxygen should be re-evaluated or continued oxygen therapy
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Detailed explanation-1: -Long-term oxygen therapy in COPD and ILD. Long-term oxygen therapy (LTOT) is typically prescribed to be used for at least 15–18 h per day for patients with resting hypoxaemia. It is a well-established intervention in patients with COPD and resting hypoxaemia.
Detailed explanation-2: -Long-term oxygen therapy (LTOT) increases survival and improves the quality of life of hypoxemic patients with chronic obstructive pulmonary disease (COPD) and is often prescribed for patients with other hypoxemic chronic lung disease [1-15].
Detailed explanation-3: -Supplemental O2 removes a COPD patient’s hypoxic (low level of oxygen) respiratory drive causing hypoventilation which causes higher carbon dioxide levels, apnea (pauses in breathing), and ultimately respiratory failure.
Detailed explanation-4: -For chronic hypoxemic patients with an arterial partial pressure of oxygen (PaO2) =55mmHg, national guidelines for LTOT recommend giving oxygen for at least 15 hours per day (4) or for 16 hours per day (5); this should be extended to 24 hours for increased efficacy (see section “Indication criteria for LTOT”) (4, 5).