MRCP UK EXAMINATIONS

RESPIRATORY

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following statements about non-invasive positive pressure mechanical ventilation for acute exacerbations of chronic obstructive pulmonary disease (COPD) is correct?
A
ineffective treatment
B
lack of evidence-based medicine
C
Can reduce the chance of intubation and mortality
D
It is effective in relieving symptoms of some patients, but cannot shorten the length of hospital stay
Explanation: 

Detailed explanation-1: -Non-invasive positive pressure ventilation involves the delivery of oxygen into the lungs via positive pressure without the need for endotracheal intubation. It is used in both acute and chronic respiratory failure but requires careful monitoring and titration to ensure its success and avoid complications.

Detailed explanation-2: -NIV is particularly indicated in: COPD with a respiratory acidosis pH 7.25–7.35 (H+ 45–56 nmol/l) Hypercapnic respiratory failure secondary to chest wall deformity (scoliosis, thoracoplasty) or neuromuscular diseases. Cardiogenic pulmonary oedema unresponsive to CPAP.

Detailed explanation-3: -Non‑invasive ventilation is used to treat persistent hypercapnic ventilatory failure and acidosis during an exacerbation of COPD, when a person’s arterial blood gases (especially the pH and carbon dioxide levels) are not responding (or worsening) despite optimal medical management.

Detailed explanation-4: -Noninvasive positive-pressure ventilation is the delivery of mechanical ventilation to patients with respiratory failure without the requirement of an artificial airway.

There is 1 question to complete.