MRCP UK EXAMINATIONS

RESPIRATORY

CYSTIC FIBROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Location where it is
A
Chromosome 9
B
Chromosome 7
C
Chromosome 1
D
Chromosome 4
Explanation: 

Detailed explanation-1: -Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 7, one copy inherited from each parent, form one of the pairs. Chromosome 7 spans about 159 million DNA building blocks (base pairs) and represents more than 5 percent of the total DNA in cells.

Detailed explanation-2: -"Chromosome 7 has long been of interest to the medical community. Besides containing many genes that are crucial to development, this chromosome also holds the gene for cystic fibrosis and is frequently damaged in some types of leukemia and other cancers, ‘’ said Francis S. Collins, M.D., Ph.

Detailed explanation-3: -Chromosome 7 also has a relatively centrally located centromere, a small region found on all chromosomes that is important during cell division. Centromeres on other chromosomes sequenced so far are located near the tip of the chromosome, like a knob.

There is 1 question to complete.