MRCP UK EXAMINATIONS

Detailed explanation-1: -People with cystic fibrosis tend to have two to five times the normal amount of salt in their sweat, so often the first CF symptom parents notice is that they taste salty when they kiss their baby.

Detailed explanation-2: -Thus, sodium and water are reabsorbed from the sweat gland tissues into the body. However, failure of the chloride channel to reabsorb chloride leads to a loss of sodium onto the skin surface and a subsequent fluid loss. This causes the pathognomonic salty skin seen with cystic fibrosis.

Detailed explanation-3: -This causes thicker, stickier mucus in the lungs and digestive system, but also results in higher levels of chloride (as salt) in sweat compared with those who do not have cystic fibrosis. Some parents who have newborn babies with CF have reported noticing that their skin tastes salty when they kiss them.

Detailed explanation-4: -Symptoms of CF Frequent lung infections including pneumonia or bronchitis. Wheezing or shortness of breath. Poor growth or weight gain in spite of a good appetite. Frequent greasy, bulky stools or difficulty with bowel movements.

Detailed explanation-5: -recurring chest infections. difficulty putting on weight. frequent, wet-sounding coughs. diarrhoea. occasional wheezing and shortness of breath. 13-Feb-2023