MRCP UK EXAMINATIONS

RESPIRATORY

OLD TUBERCULOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Patients who received anti-TB therapy had a greater proportion of successful outcomes compared to those who did not receive ATT. What is the percentage of treatment failure among patients receiving ATT?
A
5-15%
B
15-30%
C
30-45%
D
<5%
Explanation: 

Detailed explanation-1: -Treatment of new TB patients consists of a 2-month intensive phase with Isoniazid, Rifampicin, Pyrazinamide and Ethambutol followed by a 4-month continuation phase with Rifampicin and Isoniazid.

Detailed explanation-2: -The reinfection disease rate after successful treatment was estimated at 2.2 per 100 person-years.

Detailed explanation-3: -Globally in 2020 (the latest annual patient cohort for which data are available), the treatment success rate for people treated for TB with first-line regimens was 86%, and ranged among WHO regions from 71% in the European Region to 92% in the Eastern Mediterranean Region ( Fig. 3.3. 6).

Detailed explanation-4: -World Health Organization (WHO) global targets for MDR-TB treatment success and adherence are currently 75%, which is lower than the 85% target for drug-sensitive TB [1, 12], reflecting both the higher rates of mortality and barriers to treatment adherence.

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