MRCP UK EXAMINATIONS

Detailed explanation-1: -The calcified lesions seen on radiographic studies at sites of healed infection and in the local nodes are the classic lesions of primary tuberculosis, termed Ghon complexes. Irritability or failure to thrive may be the only symptoms of primary TB disease in children; weight loss also is common.

Detailed explanation-2: -Primary infection, the initial phase, occurs in people without specific immunity, generally normal children and young adults who have not previously been exposed to Mycobacterium tuberculosis. The initial infection can occur at any time during childhood, but adolescence is the peak time of risk.

Detailed explanation-3: -Primary tuberculosis in adolescents and adults tends to manifest itself as lung parenchymal lesions in the upper lobes or superior segments of the lower lobes (14, 17). In addition, pleural effusion or mediastinal lymph node enlargement is occasional.

Detailed explanation-4: -M. tuberculosis is a small, rod-shaped, strictly aerobic, acid-fast bacillus a. Acid-fast bacilli are bacilli, which once stained, resist discoloration by acid and alcohol. . Like other mycobacteria, it is slow growing, resulting in more gradual development of disease when compared with other bacterial infections.