MRCP UK EXAMINATIONS

RESPIRATORY

OLD TUBERCULOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the treatment scheme for active tuberculosis in adults and children weighing between 25 and 39 kg?
A
2 tab RHRifampicina 150 mg + Isoniazida 75 mg
B
First phase:2 tablets-Combination of RHZE*Rifampicin 150 mg + Isoniazid 75 mg+ Pyrazinamide 400 mg+ Ethambutol 275 mg-Second phase:2 tablets Combination of RHRifampicin 150 mg + Isoniazid 75 mg
C
First phase:3 tablets-Combination of RHZE*Rifampicin 150 mg + Isoniazid 75 mg+ Pyrazinamide 400 mg+ Ethambutol 275 mg-Second phase:3 tablets Combination of RHRifampicin 150 mg + Isoniazid 75 mg
D
First phase:3 tablets-Combination of RHZE*Rifampicin 150 mg +Isoniazid 75 mg+ Pyrazinamide 400 mg+ Ethambutol 275 mg
Explanation: 

Detailed explanation-1: -Rifampin and isoniazid combination is used to treat tuberculosis (TB) infection. It may be taken alone or with one or more other medicines for TB. Rifampin belongs to the class of medicines called antibiotics and works to kill or prevent the growth of bacteria.

Detailed explanation-2: -Pulmonary TB The usual treatment is: 2 antibiotics (isoniazid and rifampicin) for 6 months. 2 additional antibiotics (pyrazinamide and ethambutol) for the first 2 months of the 6-month treatment period.

Detailed explanation-3: -For initial empiric treatment of TB, start patients on a 4-drug regimen: isoniazid, rifampin, pyrazinamide, and either ethambutol or streptomycin. Once the TB isolate is known to be fully susceptible, ethambutol (or streptomycin, if it is used as a fourth drug) can be discontinued.

Detailed explanation-4: -Children over 2 years of age can be treated for latent TB infection with once-weekly isoniazid-rifapentine for 12 weeks. Alternative treatments for latent TB infection in children include 4 months of daily rifampin or 9 months of daily isoniazid.

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