AP PSYCHOLOGY

Detailed explanation-1: -The major findings are that schizophrenia is a highly polygenic disorder with a complex array of risk loci, many include genes implicated also in intellectual disability, autism spectrum disorders, bipolar disorder and major depressive disorder.

Detailed explanation-2: -Models of Genetic Transmission The monogenic model of schizophrenia was attractive for a variety of reasons, e.g., simplicity, a hope of discovering a corresponding, simple pathophysiological mechanism, and because it fitted into available theoretical options (i.e., recessive, dominant, with varying penetrance).

Detailed explanation-3: -Conclusions: The study demonstrates that an available measure of genetic risk for schizophrenia is robustly associated with schizophrenia in health care settings and has pleiotropic effects on related psychiatric disorders as well as other medical syndromes.

Detailed explanation-4: -Schizophrenia tends to run in families, but no single gene is thought to be responsible. It’s more likely that different combinations of genes make people more vulnerable to the condition. However, having these genes does not necessarily mean you’ll develop schizophrenia.