ABNORMAL BEHAVIOR
SCHIZOPHRENIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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They had x3 more receptors than controls
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They had x2 more receptors than controls
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They had x3 less receptors than controls
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They had x2 less receptors than controls
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Detailed explanation-1: -PET is an important functional imaging technique that can be used to investigate neurotransmitter receptors and transporters directly by mapping human brain function. PET is increasingly being used greatly to advance our understanding of the neurobiology and pathophysiology of schizophrenia.
Detailed explanation-2: -PET findings on drug-naïve schizophrenia patients have reported inconsistencies in D1R binding and cognitive functioning. Some studies have shown a decrease in prefrontal D1R binding (51), whereas others have shown an increase in D1R binding (49) or reported no differences between patients and controls (52).
Detailed explanation-3: -In a large clinical study, 60 percent of patients with schizophrenia (subtype 1) had decreased gray matter volumes throughout the brain compared to healthy people, which is the typical pattern seen in those with this disorder.
Detailed explanation-4: -Computerized tomography (CT) is frequently used routinely in schizophrenia, and large numbers of scans are available for study.