AP PSYCHOLOGY

Detailed explanation-1: -They inhibit dopaminergic neurotransmission in the brain by blocking about 72% of the D2 dopamine receptors . They can also block noradrenergic, cholinergic, and histaminergic activity.

Detailed explanation-2: -Dopamine antagonists turn down dopamine activity, which may be useful for the treatment of psychiatric conditions such as schizophrenia and bipolar disorder, which have been associated with an overactive dopamine system.

Detailed explanation-3: -Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists.

Detailed explanation-4: -Dopamine receptor antagonists The three classes include: phenothiazines (prochlorperazine, chlorpromazine, and promethazine), butyrophenones (droperidol and haloperidol), and metoclopramide.

Detailed explanation-5: -The traditional antipsychotic or antiemetic drugs, also called neuroleptics, block dopamine receptors and are sometimes used to treat the various hyperkinetic movement disorders.