AP PSYCHOLOGY

BIOLOGICAL BASES OF BEHAVIOR

BIOLOGICAL PSYCHOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What was used to measure the grey matter in participants brains in Maguire’s study?
A
Voxel-Based Morphometry (VBM)
B
Voxell-Morphometry Based (VMB)
C
Voxel-Morphometry Based (VMB)
D
Voxel-Based Morphomety (VBM)
Explanation: 

Detailed explanation-1: -The morphology of cortical grey matter is commonly assessed using T1-weighted MRI together with automated computerised methods such as voxel-based morphometry (VBM) and cortical thickness measures.

Detailed explanation-2: -For the grey matter volume in the surface representation, we found h2 = 0.723, SE = 0.099, p = 1.6 × 10−14 and for the voxel-based representation, h2 = 0.667, SE = 0.103, p = 2.1 × 10−12. Table 3 shows regional heritabilities, computed using data from both hemispheres.

Detailed explanation-3: -Voxel-based morphometry (VBM) is a neuroimaging technique that investigates focal differences in brain anatomy. The core process of VBM is segmenting the brain into grey matter, white matter, and cerebrospinal fluid, warping the segmented images to a template space and smoothing.

Detailed explanation-4: -At its simplest, voxel-based morphometry (VBM) involves a voxelwise comparison of regional gray matter ‘density’ between two groups of subjects. Density here refers to the relative amount of gray matter and should not be confused with cell packing density (number of cells per unit volume of neuropil).

Detailed explanation-5: -A voxel is a 3D unit of the image with a single value, just as for digital photographs a pixel is a 2D unit of the image with a single value. The words image and volume (and sometimes scan) are often used interchangeably to mean “a single 3D representation of brain data”.

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