AP PSYCHOLOGY

BIOLOGICAL BASES OF BEHAVIOR

BIOLOGY OF CONSCIOUSNESS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cocaine is a re-uptake inhibitor for this neurotransmitter?
A
norepinephrine.
B
dopamine.
C
endorphins.
D
GABA.
Explanation: 

Detailed explanation-1: -Inhibitors of the dopamine transporter, such as cocaine, will stop the reuptake of dopamine and allow it to stay extracellularly, causing prominent changes at the molecular, cellular, and behavioral levels.

Detailed explanation-2: -Nomifensine (Dual selective norepinephrine–dopamine reuptake inhibitor (NDRI) is a drug used for the treatment of clinical depression, attention deficit hyperactivity disorder (ADHD), narcolepsy, and the management of Parkinson’s disease.

Detailed explanation-3: -Cocaine inhibits the re-uptake of synaptic dopamine and serotonin, as well as norepinephrine by binding with high affinity to the serotonin transporter (SERT), dopamine transporter (DAT) and norepinephrine transporter (NET).

Detailed explanation-4: -Cocaine inhibits the reuptake of dopamine (DA), norepinephrine (NE), and serotonin (5-HT).

Detailed explanation-5: -Cocaine is a monoamine transporter blocker and, thus, an indirect agonist of dopamine receptors. Cocaine binds the dopamine transporter (DAT), blocking the protein’s ability to uptake dopamine from the synaptic cleft and also blocking DAT from terminating dopamine signaling.

There is 1 question to complete.