AP PSYCHOLOGY

Detailed explanation-1: -Cocaine potentiates acute sympathetic effects on the cardiovascular system, with consequent increased inotropic and chronotropic effects, and increased peripheral vasoconstriction causing hypertension.

Detailed explanation-2: -Cocaine affects the cardiovascular system through 2 major pathways: increased sympathetic output and a local anesthetic effect. Through increased sympathetic tone and catecholamine levels, cocaine increases heart rate, blood pressure, and myocardial contractility, all of which increase myocardial oxygen demand.

Detailed explanation-3: -History of misuse or addiction: Intentionally misusing prescription drugs or using illicit drugs can put you at risk of a drug overdose, particularly if it happens often or if you become addicted. This risk increases if you use multiple drugs, mix different drugs, or use them with alcohol.

Detailed explanation-4: -Other potential causes of stroke include hypotension and hypoxemia induced by opiate overdose; these can result in global hypoxic-ischemic injury to classically vulnerable areas of the brain (Andersen and Skullerud 1999).