AP PSYCHOLOGY

BIOLOGICAL BASES OF BEHAVIOR

NEUROTRANSMISSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is classified as an antagonist?
A
Cocaine, because it floods the brain with dopamine
B
Mescaline, because it floods the brain with dopamine
C
An amphetamine, because they lead to increased central nervous system activity
D
A tricyclic antidepressant, because they block serotonin and norepinephrine transporters
E
ProzacĀ®, because it blocks the reuptake of serotonin
Explanation: 

Detailed explanation-1: -The Food and Drug Administration (FDA) approved these tricyclic antidepressants to treat depression: Amitriptyline. Amoxapine. Desipramine (Norpramin)

Detailed explanation-2: -The tricyclic antidepressants amitriptyline, nortriptyline and imipramine are weak antagonists of human and rat alpha1B-adrenoceptors. Neuropharmacology.

Detailed explanation-3: -Tricyclic antidepressants act on approximately five different neurotransmitter pathways to achieve their effects. They block the reuptake of serotonin and norepinephrine in presynaptic terminals, which leads to increased concentration of these neurotransmitters in the synaptic cleft.

Detailed explanation-4: -Tricyclic antidepressants increase levels of norepinephrine and serotonin, two neurotransmitters, and block the action of acetylcholine, another neurotransmitter.

There is 1 question to complete.